Predominant suppression of apoptosome by inhibitor of apoptosis protein in non-small cell lung cancer H460 cells: therapeutic effect of a novel polyarginine …

L Yang, T Mashima, S Sato, M Mochizuki, H Sakamoto… - Cancer research, 2003 - AACR
… selectively reversed the apoptosis resistance of H460 cells, and … -dependent suppression
of apoptosome predominantly occurs … cell death induced by chemotherapy in vitro and in vivo. …

Role of autophagy and apoptosis in non-small-cell lung cancer

G Liu, F Pei, F Yang, L Li, AD Amin, S Liu… - International journal of …, 2017 - mdpi.com
… of caspases and removal of the N-terminal inhibitory domain, … -9, another apoptosis protein
associated with apoptosome … In addition, the predominant apoptotic protein caspase-3 also …

[HTML][HTML] Proteasome inhibition sensitizes nonsmall cell lung cancer to histone deacetylase inhibitor–induced apoptosis through the generation of reactive oxygen …

CE Denlinger, BK Rundall, DR Jones - The Journal of Thoracic and …, 2004 - Elsevier
… that direct inhibition of NF-κB with a dominant negative IκB, … determine whether bortezomib
could suppress such a dramatic … to apoptosis in cells capable of forming the apoptosome but …

Osthole induces lung cancer cell apoptosis through inhibition of inhibitor of apoptosis family proteins

XM Xu, ML Zhang, Y Zhang, L Zhao - Oncology Letters, 2016 - spandidos-publications.com
… the apoptosis of nonsmall cell lung cancer (NSCLC) cells and … both Osthole and Embelin
inhibited cell proliferation. Notably, … suppressed migration and invasion, and induced apoptosis

Differential sensitivity to apoptosome apparatus activation in non-small cell lung carcinoma and the lung

E Moravcikova, E Krepela… - International …, 2014 - spandidos-publications.com
inhibitor of apoptosis (XIAP) in the regulation of apoptosomesuppress the activity of
apoptosome apparatus in NSCLCs. … (T and I) and was the predominant finding in the majority of …

Expression of inhibitor of apoptosis proteins in small-and non-small-cell lung carcinoma cells

J Ekedahl, B Joseph, MY Grigoriev, M Müller… - Experimental cell …, 2002 - Elsevier
… protease activating factor 1) and procaspase-9 form the apoptosomepredominant mode of
cell death in H82 and U1810 cells. U1810 … VP16 induced a more pronounced suppression of …

… -induced caspase activation in non-small cell lung cancer cells: a small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase …

A Checinska, BSJ Hoogeland, JA Rodriguez… - Experimental cell …, 2007 - Elsevier
… -9 cleavage product accumulated predominantly, and the p35 … apoptosome-dependent
caspase-9 activation in NSCLC cells… Here we studied whether the suppression of caspase-9 and …

Expression of apoptosome pathway-related transcripts in non-small cell lung cancer

E Křepela, J Procházka, P Fiala, P Zatloukal… - Journal of cancer …, 2006 - Springer
… may be intrinsically primed for apoptosis through upregulated expression of transcripts encoding
the … pathway due to the lack of sufficient quantity of Apaf-1 protein. In fact, it was recently …

Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim

R Li, T Moudgil, HJ Ross, HM Hu - Cell Death & Differentiation, 2005 - nature.com
… -3, which predominantly occurred in detached cells (… apoptosis of our NSCLC cell lines is
caspase-dependent, CRI-619 and CRI-702 cells were incubated with cell-permeable inhibitors

Correspondence re: L. Yang et al., Predominant Suppression of Apoptosome by Inhibitor of Apoptosis Protein in Non-Small Cell Lung Cancer H460 Cells: Therapeutic Effect of a …

FAE Kruyt, A Checinska, G Giaccone, CG Ferreira - Cancer research, 2003 - AACR
… Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondriacontrolled
manner in the non-small-cell lung cancer cell line NCI-H460. Cancer Res., 60: 7133–7141, …