Premotor cortex modulates somatosensory cortex during voluntary movements without proprioceptive feedback

MS Christensen, J Lundbye-Jensen, SS Geertsen… - Nature …, 2007 - nature.com
Nature neuroscience, 2007nature.com
Movement perception relies on sensory feedback, but the involvement of efference copies
remains unclear. We investigated movements without proprioceptive feedback using
ischemic nerve block during fMRI in healthy humans, and found preserved activation of the
primary somatosensory cortex. This activation was associated with increased interaction
with premotor cortex during voluntary movements, which demonstrates that perception of
movements relies in part on predictions of sensory consequences of voluntary movements …
Abstract
Movement perception relies on sensory feedback, but the involvement of efference copies remains unclear. We investigated movements without proprioceptive feedback using ischemic nerve block during fMRI in healthy humans, and found preserved activation of the primary somatosensory cortex. This activation was associated with increased interaction with premotor cortex during voluntary movements, which demonstrates that perception of movements relies in part on predictions of sensory consequences of voluntary movements that are mediated by the premotor cortex.
nature.com
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