Preparation and characterization of Au/NiPc/Anti-p53/BSA electrode for application as a p53 antigen sensor
While the tumor suppressor protein p53 regulates the cell cycle to prevent cell damage, it
also triggers apoptosis and prevents cancer. These inhibitory functions may disappear once
the p53 gene is mutated. Under these circumstances, the detection of p53 protein
concentrations can have significant clinical applications. In this study, nickel phthalocyanine
(NiPc) was coated on a gold electrode to produce a modified Au/NiPc electrode. p53
antibodies were bonded to the Au/NiPc electrode by the Ni+ 2 ion in NiPc, which can be self …
also triggers apoptosis and prevents cancer. These inhibitory functions may disappear once
the p53 gene is mutated. Under these circumstances, the detection of p53 protein
concentrations can have significant clinical applications. In this study, nickel phthalocyanine
(NiPc) was coated on a gold electrode to produce a modified Au/NiPc electrode. p53
antibodies were bonded to the Au/NiPc electrode by the Ni+ 2 ion in NiPc, which can be self …
[PDF][PDF] Preparation and Characterization of Au/NiPc/Anti-p53/BSA Electrode for Application as a p53 Antigen Sensor. Chemosensors 2021, 9, 17
YJ Chen, YR Peng, HY Lin, TY Hsueh, CS Lai, MY Hua - 2021 - academia.edu
While the tumor suppressor protein p53 regulates the cell cycle to prevent cell damage, it
also triggers apoptosis and prevents cancer. These inhibitory functions may disappear once
the p53 gene is mutated. Under these circumstances, the detection of p53 protein
concentrations can have significant clinical applications. In this study, nickel phthalocyanine
(NiPc) was coated on a gold electrode to produce a modified Au/NiPc electrode. p53
antibodies were bonded to the Au/NiPc electrode by the Ni+ 2 ion in NiPc, which can be self …
also triggers apoptosis and prevents cancer. These inhibitory functions may disappear once
the p53 gene is mutated. Under these circumstances, the detection of p53 protein
concentrations can have significant clinical applications. In this study, nickel phthalocyanine
(NiPc) was coated on a gold electrode to produce a modified Au/NiPc electrode. p53
antibodies were bonded to the Au/NiPc electrode by the Ni+ 2 ion in NiPc, which can be self …
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