[HTML][HTML] Preparation and characterization of biodegradable glimepiride loaded PLA Nanoparticles by o/w solvent evaporation method using high pressure …

VJ Mokale, JB Naik, U Verma… - SAJ Pharmacy and …, 2014 - fulltext.scholarena.co
Glimepiride is used for the treatment of type 2 diabetes mellitus, one of the third generation
sulfonylurea drugs having poor aqueous solubility, slow dissolution rate and low elimination
half life. The Aim of the present study was to prepare Glimepiride loaded poly-D, L-lactide
(PLA) Nanoparticles by o/w solvent evaporation method using high speed homogenizer.
Prepared Nanoparticles were characterized for the drug content, encapsulation efficiency.
Physical state of the drug, polymer and Nanoparticles were determined by Particle size …

[PDF][PDF] Preparation and characterization of Biodegradable Glimepiride Loaded PLA Nanoparticles by o/w Solvent Evaporation method using high pressure …

VJ Mokale, JB Naik, U Verma, JS Patil, SK Yadava - Article history, 2014 - researchgate.net
Glimepiride is used for the treatment of type 2 diabetes mellitus, one of the third generation
sulfonylurea drugs having poor aqueous solubility, slow dissolution rate and low elimination
half life. The Aim of the present study was to prepare Glimepiride loaded poly-D, L-lactide
(PLA) Nanoparticles by o/w solvent evaporation method using high speed homogenizer.
Prepared Nanoparticles were characterized for the drug content, encapsulation efficiency.
Physical state of the drug, polymer and Nanoparticles were determined by Particle size …
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