Preparation and characterization of sodium alginate/polyvinyl alcohol hydrogel containing drug-loaded chitosan nanoparticles as a drug delivery system
In this study, an optimal combination of sodium alginate (SA)/polyvinyl alcohol (PVA)
hydrogel containing Rosuvastatin-loaded chitosan (CS) nanoparticles was fabricated as the
drug delivery system (DDS). First, the drug-loaded nanoparticles were synthesized by the
ionic gelation method. Then, several hydrogel films with different ratios of SA: PVA were
prepared. Subsequently, different concentrations of drug-loaded CS nanoparticles were
added to a hydrogel with an optimal SA: PVA ratio. The results of the tensile test showed that …
hydrogel containing Rosuvastatin-loaded chitosan (CS) nanoparticles was fabricated as the
drug delivery system (DDS). First, the drug-loaded nanoparticles were synthesized by the
ionic gelation method. Then, several hydrogel films with different ratios of SA: PVA were
prepared. Subsequently, different concentrations of drug-loaded CS nanoparticles were
added to a hydrogel with an optimal SA: PVA ratio. The results of the tensile test showed that …
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