Preparation of hexafluoroisopropyl esters by oxidative esterification of aldehydes using sodium persulfate

AL Sandoval, F Politano, ML Witko… - Organic & Biomolecular …, 2021 - pubs.rsc.org
AL Sandoval, F Politano, ML Witko, NE Leadbeater
Organic & Biomolecular Chemistry, 2021pubs.rsc.org
A simple, metal-free route for the oxidative esterification of aldehydes to yield
hexafluoroisopropyl esters is reported. The methodology employs sodium persulfate and a
catalytic quantity of a nitroxide and is applicable to aromatic, heteroaromatic, and aliphatic
aldehydes.
A simple, metal-free route for the oxidative esterification of aldehydes to yield hexafluoroisopropyl esters is reported. The methodology employs sodium persulfate and a catalytic quantity of a nitroxide and is applicable to aromatic, heteroaromatic, and aliphatic aldehydes.
The Royal Society of Chemistry
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