[HTML][HTML] Presynaptic M2 muscarinic receptors are involved in controlling the kinetics of ACh release at the frog neuromuscular junction

I Slutsky, I Silman, I Parnas, H Parnas - The Journal of Physiology, 2001 - ncbi.nlm.nih.gov
I Slutsky, I Silman, I Parnas, H Parnas
The Journal of Physiology, 2001ncbi.nlm.nih.gov
… To date, however, there has been no direct demonstration that the inhibitory autoreceptor
plays a role in control of the time course of release. We demonstrate here that the
presynaptic M 2 receptor at the frog neuromuscular junction is indeed involved in control of
the time course of release. Furthermore, we check one of the consequences of the
hypothesis outlined above (Parnas et al. 2000). Specifically, the hypothesis predicts that
after evoked … In this study, experiments were designed to test the possibility that …
Abstract
1. Macropatch recording was used to study release of acetylcholine in the frog neuromuscular junction evoked by either direct local depolarization or by an action potential.
ncbi.nlm.nih.gov
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