Prevention and reversal of nitrate tolerance in patients with congestive heart failure
M Packer, WH Lee, PD Kessler… - … England Journal of …, 1987 - Mass Medical Soc
To evaluate possible mechanisms underlying the development of nitrate tolerance, we
treated 35 patients who had severe chronic heart failure with a prolonged (48-hour)
intravenous infusion of nitroglycerin (6.4 μg per kilogram of body weight per minute) given
either continuously or intermittently (12-hour infusions separated by intervals of 12 hours).
Intravenous nitroglycerin produced immediate hemodynamic benefits in all patients, but the
magnitude of this improvement was greatly diminished after 48 hours of continuous therapy …
treated 35 patients who had severe chronic heart failure with a prolonged (48-hour)
intravenous infusion of nitroglycerin (6.4 μg per kilogram of body weight per minute) given
either continuously or intermittently (12-hour infusions separated by intervals of 12 hours).
Intravenous nitroglycerin produced immediate hemodynamic benefits in all patients, but the
magnitude of this improvement was greatly diminished after 48 hours of continuous therapy …
Prevention and Reversal of Nitrate Tolerance in Patients with Congestive Heart Failure
M PACKER, W LEE, P KESSLER… - Survey of …, 1988 - journals.lww.com
Prevention and Reversal of Nitrate Tolerance in Patients wit... : Survey of Anesthesiology
Prevention and Reversal of Nitrate Tolerance in Patients with Congestive Heart Failure :
Survey of Anesthesiology Log in or Register Subscribe to journalSubscribe Get new issue
alertsGet alerts Secondary Logo Journal Logo Advanced Search Toggle navigation Subscribe
Register Login Articles & Issues For Authors Journal Info Advanced Search April 1988 -
Volume 32 - Issue 2 Previous Abstract Next Abstract PHARMACOLOGY: PDF Only Prevention …
Prevention and Reversal of Nitrate Tolerance in Patients with Congestive Heart Failure :
Survey of Anesthesiology Log in or Register Subscribe to journalSubscribe Get new issue
alertsGet alerts Secondary Logo Journal Logo Advanced Search Toggle navigation Subscribe
Register Login Articles & Issues For Authors Journal Info Advanced Search April 1988 -
Volume 32 - Issue 2 Previous Abstract Next Abstract PHARMACOLOGY: PDF Only Prevention …