… Translation to clinical use has begun, with encouraging results from a … vaccination in humans.
This work highlights the value of a prime-target approach for immunization against malaria …

… LAGAP immunization are required for protection against BS … , are protective targets and
thus could be prime candidates for … resulting from LAGAP immunization is targeting protective …

… ggCSP-immunized mice were not sterilely protected from challenge … against de novo–expressed
liver-stage Ags (36, 51). … the DNA vaccine with the inherent tissue-targeting properties of …

… and immunity against liver stage Plasmodium infection. … −/− mice will result in adaptive
immune protection against … of Mdr2 −/− mice as a mouse model for malaria infection allowed us to …

… superior protection in inbred and outbred mice compared to … next-generation live-attenuated
malaria vaccines and support … Although protection against sporozoite challenge increased …

… two groups, those naturally protected from the pathogen and those susceptible. By … Murine
Plasmodium species are commonly used to study the liver-stage of infection in mice and in …

… development of protective human vaccine targeting clinically … % of prime-boosted outbred
mice were sterilely protected against … protection induced upon vaccination with late-liver-stage-…

… We find that liver-stage malaria-specific memory CD8 T cells primed by weight-adjusted
RAS vaccination can be numerically … Prime and target immunization protects against liver-stage …

… reduces liver stage burden in vivo, contributes to the protection … from mice immunized with
Pyfabb/f − as well as from mock-… whole parasite immunization protects against malaria, thus …

… mice immunized with radiation-attenuated sporozoites (RAS) demonstrated sterile immune
protection against malaria … (CPS vaccines), which acts on blood stage but not liver-stage …