This research aims to describe the factors and patterns of relationships involved in dominant professional skills development by focusing on social skills that influence organizational learning for business sustainability and operational efficiency enhancement. The research provides guidelines that hotel businesses in Phuket Province can use to implement strategies in a currently rapidly-changing and competitive environment. This study shows that professional and social skills influencing the organizational performance of the hotel businesses in Phuket include communication, leadership, problem solving, and teamwork skill. This analytical result is based on resource -based and service innovation theories and can be used to improve organizations operating performance.