Profiles of prognostic alternative splicing signature in hepatocellular carcinoma

F Wu, Q Chen, C Liu, X Duan, J Hu, J Liu… - Cancer …, 2020 - Wiley Online Library
… Overview of the seven types of alternative splicing in this study. UpSet plot of interactions of
… of alternative splicing (AS) events (A) with differential AS events in hepatocellular carcinoma (…

Systematic profiling of a novel prognostic alternative splicing signature in hepatocellular carcinoma

D Zhang, Y Duan, Z Wang, J Lin - Oncology Reports, 2019 - spandidos-publications.com
… The integrated mRNA sequencing data of 290 patients with HCC with AS events profiles
were included in the present study. The median follow-up period was 15.75 months (range 1–…

Prognostic alternative mRNA splicing signature in hepatocellular carcinoma: a study based on large-scale sequencing data

GQ Zhu, YJ Zhou, LX Qiu, B Wang, Y Yang… - …, 2019 - academic.oup.com
… that alternative splicing (AS) is modified and related to tumorprofiles of AS signature in
hepatocellular carcinoma (HCC) is … spliced AS transcripts between HCC and non-HCC tissues …

Immunological significance of prognostic alternative splicing signature in hepatocellular carcinoma

Q Xu, H Xu, R Deng, N Li, R Mu, Z Qi, Y Shen… - Cancer cell …, 2021 - Springer
prognostic signature and elucidate the role in tumor immune microenvironment (TIME) and
immunotherapy in HCC… a LASSO coefficient profiles of the whole AS events. b Ten‐time cross…

Prognostic index of aberrant mRNA splicing profiling acts as a predictive indicator for hepatocellular carcinoma based on TCGA SpliceSeq data

HY Wu, ZG Peng, RQ He, B Luo… - International …, 2019 - spandidos-publications.com
alternative splicing event profiles of 371 patients with HCCprognostic model based on
HCC‑specific alternative splicing … More importantly, the prognostic signature based on splicing

Genome-wide transcriptional analysis reveals alternative splicing event profiles in hepatocellular carcinoma and their prognostic significance

Y Xiong, G Yang, K Wang, M Riaz, J Xu, Z Lv… - Frontiers in …, 2020 - frontiersin.org
Prognostic value of differentially expressed alternative splicing (DEAS) in hepatocellular
carcinoma. Part DEAS events simultaneously associated with overall survival (OS) and disease-…

[HTML][HTML] An alternative splicing signature model for predicting hepatocellular carcinoma-specific survival

S Dong, LJ Lu - Journal of Gastrointestinal Oncology, 2020 - ncbi.nlm.nih.gov
… We generated AS profiles in HCC patients in TCGA. In this cohort, we … prognostic signature
for HCC patients. We consider these findings to be reliable and valuable for HCC prognosis. …

Prognostic alternative mRNA splicing signature in non-small cell lung cancer

Y Li, N Sun, Z Lu, S Sun, J Huang, Z Chen, J He - Cancer letters, 2017 - Elsevier
… of splicing associated with cancer. Genome-wide alternative splicing profiling in lung cancer
… We generated alternative splicing profiles in 491 lung adenocarcinoma (LUAD) and 471 …

Identification of prognostic alternative splicing events related to the immune microenvironment of hepatocellular carcinoma

S Yu, L Cai, C Liu, R Gu, L Cai, L Zhuo - Molecular Medicine, 2021 - Springer
… By comparing transcriptional expression profiles in 370 HCC … Furthermore, the final prognostic
signature was established, … Some genes in our prognostic signature model have been …

A novel 16-gene alternative mRNA splicing signature predicts tumor relapse and indicates immune activity in stage I–III hepatocellular carcinoma

XX Chen, BH Zhang, YC Lu, ZQ Li, CY Chen… - Frontiers in …, 2022 - frontiersin.org
Hepatocellular carcinoma (HCC) is a lethal disease with high relapse and dismal survival
rates. Alternative splicing (AS) plays a crucial role in tumortumor relapse or prognosis of HCC. …