Prognostic value of tissue polyamine levels in human colorectal carcinoma.
M Linsalata, MG Caruso, S Leo, V Guerra… - Anticancer …, 2002 - europepmc.org
Anticancer research, 2002•europepmc.org
Background Polyamines are aliphatic cations that play critical roles in cell proliferation and
differentiation and in cancer development. Abnormally high polyamine levels have been
demonstrated in various types of cancer, but few studies have investigated the prognostic
significance of tissue polyamine levels. In this study we evaluated the disease-free survival
of patients with colorectal adenocarcinoma according to the polyamine levels in neoplastic
tissue and uninvolved surrounding mucosa.
differentiation and in cancer development. Abnormally high polyamine levels have been
demonstrated in various types of cancer, but few studies have investigated the prognostic
significance of tissue polyamine levels. In this study we evaluated the disease-free survival
of patients with colorectal adenocarcinoma according to the polyamine levels in neoplastic
tissue and uninvolved surrounding mucosa.
Background
Polyamines are aliphatic cations that play critical roles in cell proliferation and differentiation and in cancer development. Abnormally high polyamine levels have been demonstrated in various types of cancer, but few studies have investigated the prognostic significance of tissue polyamine levels. In this study we evaluated the disease-free survival of patients with colorectal adenocarcinoma according to the polyamine levels in neoplastic tissue and uninvolved surrounding mucosa.
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