Prolactin-releasing peptide activation of the prolactin promoter is differentially mediated by extracellular signal-regulated protein kinase and c-Jun N-terminal protein …

A Kimura, M Ohmichi, K Tasaka, Y Kanda… - Journal of Biological …, 2000 - ASBMB
Regulation of the mitogen-activated protein kinase (MAPK) family by prolactin-releasing
peptide (PrRP) in both GH3 rat pituitary tumor cells and primary cultures of rat anterior
pituitary cells was investigated. PrRP rapidly and transiently activated extracellular signal-
regulated protein kinase (ERK) in both types of cells. Both pertussis toxin, which inactivates
G i/G o proteins, and exogenous expression of a peptide derived from the carboxyl terminus
of the β-adrenergic receptor kinase I, which specifically blocks signaling mediated by the βγ …
以上显示的是最相近的搜索结果。 查看全部搜索结果