Teachers and other school staff play key roles as partners in the prevention, identification, and intervention of mental health difficulties among children and youth. However, it is essential that teachers are equipped with sufficient mental health literacy to engender effective practices in these areas. This article reviews the literature related to mental health literacy with respect to the perceived preparedness of teachers as well as approaches that have been taken or are under way to improve literacy. A specific focus on bullying is also highlighted. Finally, suggestions emerging from current research as to the elements of effective approaches to teacher preparation are explored as well as recommendations for future research in the area.