Prophylactic radiation therapy vs. standard-of-care for patients with high-risk, asymptomatic bone metastases: a multicenter, randomized phase II trial

EF Gillespie, NJ Mathis, C Marine, Z Zhang… - … of Radiation Oncology …, 2022 - redjournal.org
… External beam radiotherapy (RT) is standard-of-care (SOC) for pain relief of symptomatic
bone metastases. We aimed to test whether radiation for asymptomatic bone metastases …

Prophylactic radiation therapy versus standard of care for patients with high-risk asymptomatic bone metastases: a multicenter, randomized phase II clinical trial

EF Gillespie, JC Yang, NJ Mathis, CB Marine… - … of Clinical Oncology, 2024 - ascopubs.org
… study, we hypothesized that radiation to asymptomatic high-risk bone metastases would
reduce SRE. Secondarily, we evaluated hospitalizations, overall survival (OS), patient-reported …

Prophylactic Radiation Therapy for High-Risk Asymptomatic Bone Metastases: A New Standard of Care or Need for More Data?

AW Chan, CB Simone, Y van der Linden… - … of Clinical Oncology, 2024 - ascopubs.org
… et al 1 on prophylactic radiation therapy (RT) for high-risk asymptomatic bone metastases.
This multicenter, randomized phase II trial demonstrated that prophylactic RT could reduce …

Prophylactic Radiation Therapy Versus Standard of Care for Patients With High-Risk Asymptomatic Bone Metastases

M Guhlich, S Rieken - Strahlentherapie und Onkologie: Organ der …, 2024 - europepmc.org
… Gillespie EF et al Prophylactic Radiation Therapy Versus Standard of Care for Patients With
High-Risk Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Clinical Trial…

Early palliative radiation versus observation for high-risk asymptomatic or minimally symptomatic bone metastases: study protocol for a randomized controlled trial

DB Rosen, CD Benjamin, JC Yang, C Doyle, Z Zhang… - BMC cancer, 2020 - Springer
… either standard of care (Arm 1) or early radiation therapy (Arm 2) … high risk for fracture
requiring surgical intervention. Upfront preventive RT that is not considered part of standard of care

Prophylactic Radiotherapy Of MInimally Symptomatic Spinal Disease (PROMISSeD): study protocol for a randomized controlled trial

RJ Rothrock, A Ozair, MC Avendano, S Herrera… - Trials, 2024 - Springer
… In this study, 78 patients with 122 high-risk bone metastases … standard-of-care systemic
therapy or upfront, early RT to … understand the role of early radiation therapy in the treatment of …

Cost-Effectiveness of Prophylactic Radiation in Patients with Asymptomatic Bone Metastases

A Dornisch, JD Murphy - International Journal of Radiation Oncology …, 2023 - redjournal.org
patients with high-risk asymptomatic bone metastasis who received either … patients with
asymptomatic bone metastases, we found that compared to standard of care, radiation therapy

[HTML][HTML] A phase II trial on radiotherapy for high-risk asymptomatic bone metastases—creating more questions than answers?

AW Chan, CB Simone II… - Annals of Palliative …, 2024 - apm.amegroups.org
… of asymptomatic high-risk bone metastasis vs. standard of care (SOC) alone in patients with
… , may provide further data on prophylactic RT of minimally symptomatic bone metastasis (27)…

Metastasis-Directed Therapy: A Moving Target Advancing Progress Forward

MP Deek, PT Tran, SK Jabbour - Journal of Clinical Oncology, 2024 - ascopubs.org
… , and palliative radiation therapy for pain, and, in turn, may improve patient survival. Such …
prophylactic radiation versus standard-of-care therapy in patients with high-risk asymptomatic

… recurrence of colorectal cancer157 Clinical research in surgical oncology: an analysis of clinicaltrials. gov158 Radiation therapy after breast conserving surgery …

R Fayez, A AlMuntashery, G Bodie, A Almamar, RS Gill… - 2012 - canjsurg.ca
Laparoscopic Roux-en-Y gastric bypass (LRYGB) is a well established standard of care in
the treatment of obesity and its associated comorbidities. Laparoscopic sleeve gastrectomy (…