Identifying prostate cancer patients that are harboring aggressive forms of prostate cancer
remains a significant clinical challenge. Here we develop an approach based on
multispectral deep-ultraviolet (UV) microscopy that provides novel quantitative insight into
the aggressiveness and grade of this disease, thus providing a new tool to help address this
important challenge. We find that UV spectral signatures from endogenous molecules give
rise to a phenotypical continuum that provides unique structural insight (ie, molecular maps …

Identifying prostate cancer patients that are harboring aggressive forms of prostate cancer
remains a significant clinical challenge. To shed light on this problem, we develop an
approach based on multispectral deep-ultraviolet (UV) microscopy that provides novel
quantitative insight into the aggressiveness and grade of this disease. First, we find that UV
spectral signatures from endogenous molecules give rise to a phenotypical continuum that
differentiates critical structures of thin tissue sections with subcellular spatial resolution …