Protection of rat liver microsomes against carbon tetrachloride-induced lipid peroxidation by red ginseng saponin through cytochrome P450 inhibition

HJ Kim, YJ Chun, JD Park, SI Kim, JK Roh… - Planta …, 1997 - thieme-connect.com
… Dawley rats (7). In … protection against CCI4-induced lipid peroxidation by the standardized
total saponin was investigated in liver microsomes prepared from male Sprague Dawley rats. …

Carbon tetrachloride-induced protection against carbon tetrachloride toxicity: The role of the liver microsomal drug-metabolizing system

EA Glende Jr - Biochemical Pharmacology, 1972 - Elsevier
… The lipid peroxidation in turn is believed to be initiated by free radicals arising from metabolism
of carbon … in the liver endoplasmic reticulum.**g Numerous reports have indicated that …

Prevention of carbon tetrachloride-induced lipid peroxidation in liver microsomes from dehydroepiandrosterone-pretreated rats

M Aragno, E Tamagno, G Poli, G Boccuzzi… - Free radical …, 1994 - Taylor & Francis
… the decrease of glucose-6-phosphatase and gammaglutamyltranspetidase, targets of lipid
protection against CC1,-dependent lipid peroxidation triggered in isolated rat liver microsomes

Protection by diethyldithiocarbamate against carbon tetrachloride lethality in rats and against carbon tetrachloride-induced lipid peroxidation in vitro

LM Lutz, EA Glende Jr, RO Recknagel - Biochemical Pharmacology, 1973 - Elsevier
Rat liver microsome-supernatant or microsome fractions were obtained and incubated as
previously reported.g The degree of lipid peroxidation was … of lipid peroxidation by carbon

Carbon tetrachloride-induced lipid peroxidation of rat liver microsomes in vitro

Y Masuda, T Murano - Biochemical Pharmacology, 1977 - Elsevier
protect against the liver damage in oivo [l, 29-311 as well as microsomal lipid peroxidation
… of halogenated hydrocarbons to produce hepatic lesion or stimulate lipid ~roxidation can be …

… of oxygen and glutathione in protection against carbon tetrachloride-induced hepatic microsomal lipid peroxidation and covalent binding in the rat. Rationale for the …

RF Burk, JM Lane, K Patel - The Journal of clinical …, 1984 - Am Soc Clin Investig
… Effect of 02concentration and GSH on CHC13 production from CC14 (A) and CCl,-induced
lipid peroxidation (B) in rat liver microsomes. Open bars indicate that no GSH was present; …

Inhibition of carbon tetrachlorideinduced lipid peroxidation by novel antioxidants in rat hepatic microsomes: Dissociation from hepatoprotective effects in vivo

GHI Wolfgang, RA Jolly, WJ Donarski… - Journal of …, 1990 - Wiley Online Library
… complete protection from lipid peroxidation in vitro, the same agents provided only partial or
no protection against toxicity in vivo. This suggests that CC1,-induced lipid peroxidation and …

Reduced glutathione protection against rat liver microsomal injury by carbon tetrachloride. Dependence on O2

RF Burk, K Patel, JM Lane - Biochemical Journal, 1983 - portlandpress.com
… on carbon tetrachloride metabolism by rat liver microsomes and on carbon tetrachloride-induced
injury to the microsomes… inhibition of carbon tetrachloride-induced lipid peroxidation are …

Postulated carbon tetrachloride mode of action: a review

MK Manibusan, M Odin… - Journal of Environmental …, 2007 - Taylor & Francis
… on lipid peroxidation and liver fibrogenesis in male Wistar rats … of carbon tetrachloride by
isolated rat liver microsomes (… a major role in carbon tetrachloride-induced liver necrosis. …

Carbon tetrachloride-induced hepatotoxicity: a classic model of lipid peroxidation and oxidative stress

S Basu - Studies on experimental models, 2011 - Springer
… is mediated through microsomal lipid peroxidation [5, 43, 44], … Carbon tetrachloride-induced
oxidative stress has been … 4 -induced lipid peroxidation and also to further study protective