[HTML][HTML] Protective effects of amlodipine on ischemia-reperfusion injury of rat ovary: biochemical and histopathologic evaluation
OBJECTIVE: To evaluate the effects of amlodipine as an antioxidant and analyze the
histopathologic changes in experimental ischemic and ischemic-reperfusion (I/R) injury in
rat ovaries. DESIGN: Experimental study. SETTING: Experimental surgery laboratory.
ANIMAL (S): Forty-two rats with experimentally induced ovarian torsion. INTERVENTION (S):
Group 1: sham operation; group 2: bilateral ovarian ischemia; group 3: 3-hour period of
ischemia plus 3 hours of reperfusion; groups 4 and 5: amlodipine administration at 3 and 5 …
histopathologic changes in experimental ischemic and ischemic-reperfusion (I/R) injury in
rat ovaries. DESIGN: Experimental study. SETTING: Experimental surgery laboratory.
ANIMAL (S): Forty-two rats with experimentally induced ovarian torsion. INTERVENTION (S):
Group 1: sham operation; group 2: bilateral ovarian ischemia; group 3: 3-hour period of
ischemia plus 3 hours of reperfusion; groups 4 and 5: amlodipine administration at 3 and 5 …