Protein Kinase C-and Reactive Oxygen Species-Dependent Stimulation of Intracellular cAMP in Human Eosinophils: The Role of Extracellular Signal-Regulated …
CI Ezeamuzie, N Taslim - Medical Principles and Practice, 2008 - karger.com
Objective: The objective of this study was to investigate the role of the extracellular signal-
regulated protein kinases 1 and 2 (ERK1/2) in the signalling pathway of the novel protein
kinase C (PKC)-and reactive oxygen species (ROS)-dependent stimulation of intracellular
adenosine 3′, 5′-cyclic monophosphate (cAMP) production in human eosinophils.
Materials and Methods: Immunomagnetically purified human eosinophils were stimulated in
vitro with a PKC activator, phorbol myristate acetate (PMA), and the cAMP response in the …
regulated protein kinases 1 and 2 (ERK1/2) in the signalling pathway of the novel protein
kinase C (PKC)-and reactive oxygen species (ROS)-dependent stimulation of intracellular
adenosine 3′, 5′-cyclic monophosphate (cAMP) production in human eosinophils.
Materials and Methods: Immunomagnetically purified human eosinophils were stimulated in
vitro with a PKC activator, phorbol myristate acetate (PMA), and the cAMP response in the …
Protein kinase C-and reactive oxygen species-dependent stimulation of intracellular CAMP in human eosinophils
E Charles I, T Najla - 2008 - pesquisa.bvsalud.org
The objective of this study was to investigate the role of the extracellular signal-regulated
protein kinases 1 and 2 [ERK1/2] in the signalling pathway of the novel protein kinase C
[PKC]-and reactive oxygen species [ROS]-dependent stimulation of intracellular adenosine
3', 5'-cyclic monophosphate [cAMP] production in human eosinophils. Immunomagnetically
purified human eosinophils were stimulated in vitro with a PKC activator, phorbol myristate
acetate [PMA], and the cAMP response in the presence of a phosphodiesterase inhibitor …
protein kinases 1 and 2 [ERK1/2] in the signalling pathway of the novel protein kinase C
[PKC]-and reactive oxygen species [ROS]-dependent stimulation of intracellular adenosine
3', 5'-cyclic monophosphate [cAMP] production in human eosinophils. Immunomagnetically
purified human eosinophils were stimulated in vitro with a PKC activator, phorbol myristate
acetate [PMA], and the cAMP response in the presence of a phosphodiesterase inhibitor …