Methods Twenty-one patients with chronic schizophrenia underwent a daily, 6-month
aerobic training program. We divided them into a group that completed the program (12
patients) and a second group that left the training program (9 patients). The biochemical and
clinical data of each patient were analyzed and the proteomic profile of the plasma was
studied using ESI-LC-MS/MS. Results Proteomic analysis recognizes 21.165 proteins and
peptides in each patient, of which we identified 1.812 proteins that varied between both …

Introduction Schizophrenia is a chronic illness often accompanied by metabolic disorders,
diabetes, obesity and cardiovascular problems often associated with unhealthy lifestyles, as
well as neuroendocrine problems caused by the disease itself. Lifestyle changes, such as
regular physical exercise, have a positive effect on metabolic disorders and mental health,
although the molecular changes that occur in this type of patient and how they explain the
changes in their response are unknown. This study wants to analyze in a novel way the …