Psychopharmacology of the hallucinogenic sage Salvia divinorum

TE Prisinzano - Life sciences, 2005 - Elsevier
Life sciences, 2005Elsevier
At present, the Mexican mint Salvia divinorum is an unregulated hallucinogen. This has
resulted in various on-line botanical companies advertising and selling S. divinorum as a
legal alternative to other regulated plant hallucinogens. It is predictable that its misuse will
increase rapidly. The active ingredient in S. divinorum is the neoclerodane diterpene,
salvinorin A (1a), which has been shown to be a κ agonist both in vitro and in vivo. This
review will cover the current state of research into the psychopharmacology of S. divinorum.
At present, the Mexican mint Salvia divinorum is an unregulated hallucinogen. This has resulted in various on-line botanical companies advertising and selling S. divinorum as a legal alternative to other regulated plant hallucinogens. It is predictable that its misuse will increase rapidly. The active ingredient in S. divinorum is the neoclerodane diterpene, salvinorin A (1a), which has been shown to be a κ agonist both in vitro and in vivo. This review will cover the current state of research into the psychopharmacology of S. divinorum.
Elsevier
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