Globally, there are challenges and threats that cannot be targeted by a single actor, even if it may be a national state, legitimized and willing to act. Hence, new collaboration regimes were created: international organizations, but also – formal or informal – cooperations with the private sector. Our paper discusses organization forms of these cooperations or ‘global public private partnerships’ (GPPP) theoretically and outlines framework conditions for the use of these global partnerships. Additionally, the health sector will be tackled exemplarily to delineate in how far GPPP are largely depending on the nature of the good provided.