Salvia officinalis (Lamiaceae) is one of the most important medicinal plants has powerful biological activity and pharmacological properties. This work reports the essential oil content and its composition of Salvia officinalis grown in Egypt, and determines their active constituents. The volatile oil content has been analyzed by GC/MS. The GC/MS revealed the presence of camphore (23.38%), α-thujone (22.82%), sclareol (10.46%), β-thujone (9.96%), 1, 8-cineole (7.83%), γ-selinene (7.73%), α-humulene (5.59%), caryophyllene,(3.16%), borneol (3.06%), limonene (1.74%) and humulene epoxide (1.02%) which represents the main compounds of volatile oil extracted from Salvia officinalis fresh herb.