Quantification of biological aging in young adults

DW Belsky, A Caspi, R Houts… - Proceedings of the …, 2015 - National Acad Sciences
young). However, there is skepticism about whether aging processes can be detected in
young adults … Our findings indicate that aging processes can be quantified in people still young

Measuring biological aging in humans: A quest

L Ferrucci, M Gonzalez‐Freire, E Fabbri… - Aging cell, 2020 - Wiley Online Library
… drivers of biological aging. However, reliable and valid assays for their quantification
should be developed before they can be used in human research and in clinical applications. …

Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm

DW Belsky, A Caspi, L Arseneault, A Baccarelli… - Elife, 2020 - elifesciences.org
… were associated with faster DunedinPoAm in young adults in the E-Risk Study To test if
DunedinPoAm indicated faster aging in young people with histories of exposure thought to …

Eleven telomere, epigenetic clock, and biomarker-composite quantifications of biological aging: do they measure the same thing?

DW Belsky, TE Moffitt, AA Cohen… - American journal of …, 2018 - academic.oup.com
… The implication of this analysis is that several methods proposed to quantify biological
aging in fact appear to quantify different “things.” Although each of these measures has its own …

A toolkit for quantification of biological age from blood chemistry and organ function test data: BioAge

D Kwon, DW Belsky - GeroScience, 2021 - Springer
… Methods to quantify biological aging are emerging as new measurement tools for …
Publicly available software packages to compute biological aging measurements from DNA …

Quantification of the biological age of the brain using neuroimaging

JH Cole, K Franke, N Cherbuin - Biomarkers of human aging, 2019 - Springer
… The volume containing this this chapter is testament to the breadth of research into
biological ageing across many different systems, organs, tissues and cells. Better integration of …

Testing proposed quantifications of biological aging in Taiwanese older adults

L Gaydosh, DW Belsky, DA Glei… - The Journals of …, 2020 - academic.oup.com
… Our findings suggest that algorithm methods proposed to quantify biological aging capture
similar information about morbidity, disability, and mortality when compared with these …

Association of blood chemistry quantifications of biological aging with disability and mortality in older adults

DC Parker, BN Bartlett, HJ Cohen… - The Journals of …, 2020 - academic.oup.com
adults in the United States (N = 1,374, age range = 71–102, 35% male, 52% African American).
We quantified biological aging … methods to quantify biological aging in older adults, but …

Disparities in the pace of biological aging among midlife adults of the same chronological age have implications for future frailty risk and policy

ML Elliott, A Caspi, RM Houts, A Ambler, JM Broadbent… - Nature aging, 2021 - nature.com
… , dental and pulmonary systems, and quantified age-related decline shared … biological
aging in the Dunedin Study the ‘Pace of Aging’. In a 2015 article, we quantified the Pace of Aging

Quantification of biological age as a determinant of age-related diseases in the Rotterdam Study: a structural equation modeling approach

R Waziry, L Gras, S Sedaghat, H Tiemeier… - European journal of …, 2019 - Springer
… Unlike studying single diseases, quantifying biological aging requires methods that take …
pace of aging and outcomes as cognitive decline in a homogenous sample of young adults [11]. …