Quantitative analysis of complement receptors, CR1 (CD35) and CR3 (CD11b), on neutrophils improves distinction between bacterial and viral infections in febrile …
J Nuutila, U Hohenthal, I Laitinen, P Kotilainen… - Journal of …, 2006 - Elsevier
There is an ongoing need for sensitive and specific markers of bacterial infection. In this
prospective study, standard clinical laboratory data (neutrophil count, serum C reactive
protein level, erythrocyte sedimentation rate) and quantitative flow cytometric analysis of
neutrophil complement receptors, CR1 and CR3, were obtained from 289 hospitalized
febrile patients. After microbiological confirmation or clinical diagnosis, 135 patients were
found to have either bacterial (n= 89) or viral (n= 46) infection. The patient data was …
prospective study, standard clinical laboratory data (neutrophil count, serum C reactive
protein level, erythrocyte sedimentation rate) and quantitative flow cytometric analysis of
neutrophil complement receptors, CR1 and CR3, were obtained from 289 hospitalized
febrile patients. After microbiological confirmation or clinical diagnosis, 135 patients were
found to have either bacterial (n= 89) or viral (n= 46) infection. The patient data was …