… during MVA infection of THP-1s, we first measured cell death … induced a sharp increase in
cell death, which was reversed … affect MVA-induced cell death at concentrations that blocked …

… of uninfected bystanders, or induction of caspase activity and cell death 73 via apoptosis17.
Previously, we conducted a systematic quantitative temporal proteomic analysis 74 …

… be cotranslationally or posttranslationally modified) varies … alterations from general stress
responses related to cell death … in the mechanisms for preferential viral gene expression at the …

… and subjected to quantitative proteomics analysis. We identified 311 proteins that were
significantly changed by SeV … immune responses and have elucidated the related mechanisms ( …

… The proteomics data were analyzed using Ingenuity Pathways Analysis to identify defined
… HRSV-host cell interactions, including those associated with the antiviral response and …

… segregation of cDC subsets is still incompletely defined. We reasoned that differences in …
with certain ssRNA viruses and were able to produce key antiviral cytokines, such as IFN-α. …

… the mechanisms that underpin efficient host antiviral immune … to discover post-translationally
modified peptides, which may be … Quantitative proteomic methods such as stable isotope …

… , post-translational modifications and interactions with other … to discover novel mechanisms
of host antiviral immunity. Additional … (iii) Nucleic acid sensing also leads to cell death via (a) …

… multiplexed proteomics to quantify ∼9,000 cellular proteins and ∼80% of viral proteins at
seven … Our approach thus identifies both a host antiviral factor and a viral mechanism of innate …

… : high throughput, quantitative proteomic analysis provides a … import mechanisms were
altered in HRSV-infected cells. … cellular modification in virus-infected cells. For example, a …