Quorum sensing and c-di-GMP-dependent alterations in gene transcripts and virulence-associated phenotypes in a clinical isolate of Aeromonas hydrophila
EV Kozlova, BK Khajanchi, J Sha, AK Chopra - Microbial pathogenesis, 2011 - Elsevier
Recently, we demonstrated that the LuxS-based quorum sensing (QS) system (AI-2)
negatively regulated the virulence of a diarrheal isolate SSU of Aeromonas hydrophila,
while the ahyRI-based (AI-1) N-acyl-homoserine lactone system was a positive regulator of
bacterial virulence. Thus, these QS systems had opposing effects on modulating biofilm
formation and bacterial motility in vitro models and in vivo virulence in a speticemic mouse
model of infection. In this study, we linked these two QS systems with the bacterial second …
negatively regulated the virulence of a diarrheal isolate SSU of Aeromonas hydrophila,
while the ahyRI-based (AI-1) N-acyl-homoserine lactone system was a positive regulator of
bacterial virulence. Thus, these QS systems had opposing effects on modulating biofilm
formation and bacterial motility in vitro models and in vivo virulence in a speticemic mouse
model of infection. In this study, we linked these two QS systems with the bacterial second …
以上显示的是最相近的搜索结果。 查看全部搜索结果