Background & Aims Barrett's esophagus (BE) with low-grade dysplasia (LGD) can progress
to high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC). Radiofrequency
ablation (RFA) has been shown to be an effective treatment for LGD in clinical trials, but its
effectiveness in clinical practice is unclear. We compared the rate of progression of LGD
after RFA with endoscopic surveillance alone in routine clinical practice. Methods We
performed a retrospective study of patients who either underwent RFA (n= 45) or …

This retrospective cohort study comparing radiofrequency ablation with surveillance in
Barrett's oesophagus with confirmed lowgrade dysplasia adds real clinical practice data to
the recent randomised control data, and its results are in concordance with the recent
change in British Gastroenterology Society guidelines. Oesophageal adenocarcinoma
(OAC) has a high mortality rate and an increasing incidence. Barrett's oesophagus (BO) is a
recognised precursor of OAC. Dysplasia in Barrett's tissue is the most potent prognosticator …