Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of excessive daytime sleepiness in narcolepsy

RJ Broughton, JAE Fleming, CFP George, JD Hill… - Neurology, 1997 - AAN Enterprises
… In summary, as little as a 200-mg daily dose of modafinil is an effective and well-tolerated
treatment of EDS in patients with narcolepsy. The long-term effectiveness is under evaluation. …

Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of residual excessive daytime sleepiness in the sleep apnea/hypopnea …

RN KINGSHOTT, M VENNELLE… - American Journal of …, 2001 - atsjournals.org
… found with modafinil (all p > 0.05). There was a significant reduction in CPAP use … modafinil
compared to placebo (6.3 ± 1 h/ night; 6.5 ± 1, p = 0.03). This study suggests that modafinil

Cognitive performance following Modafinil versus placebo in sleep‐deprived emergency physicians: a doubleblind randomized crossover study

M Gill, P Haerich, K Westcott… - Academic …, 2006 - Wiley Online Library
… Objectives: Modafinil has recently been approved for the treatment of shift work sleep …
Study Design This was a randomized, double-blind, placebo-controlled crossover study. We …

Modafinil for the Treatment of Daytime Sleepiness in Parkinson´ s Disease: A Double-blind, Randomized, Crossover, Placebo-controlled Polygraphic Trial

B Högl, M Saletu, E Brandauer, S Glatzl, B Frauscher… - Sleep, 2002 - academic.oup.com
… In this study, we evaluated the effect of modafinil for treatment of daytime sleepiness in PD
patients. The ESS significantly improved with modafinil compared to placebo, whereas the …

MIDAS (Modafinil in Debilitating Fatigue After Stroke) A Randomized, Double-Blind, Placebo-Controlled, Cross-Over Trial

A Bivard, T Lillicrap, V Krishnamurthy, E Holliday… - Stroke, 2017 - Am Heart Assoc
… -reported fatigue on the MFI after 6 weeks of modafinil treatment with a type I error rate of 0.05
… required for a crossover study using previously reported effects of modafinil on fatigue for …

Modafinil improves real driving performance in patients with hypersomnia: a randomized double-blind placebo-controlled crossover clinical trial

P Philip, C Chaufton, J Taillard, A Capelli, O Coste… - Sleep, 2014 - academic.oup.com
… We therefore designed a double-blind crossover study (modafinil versus placebo) to test the
… In conclusion, patients with hypersomnia treated with modafinil should be considered to be …

A randomized, double-blind, crossover trial of modafinil on mood

I Taneja, K Haman, RC Shelton… - Journal of clinical …, 2007 - journals.lww.com
study was to determine how treatment with modafinil … , randomized, crossover, inpatient trial
of modafinil (400 mg daily) versus placebo with 4-day washout period between 2 treatments. …

… daytime sleepiness in patients with mild to moderate obstructive sleep apnoea not using standard treatments: a randomised placebo-controlled crossover trial

JL Chapman, L Kempler, CL Chang, SC Williams… - Thorax, 2014 - thorax.bmj.com
… . Modafinil effects during acute continuous positive airway pressure withdrawal: a randomized
crossover double-blind placebo-controlled trial. Am J Respir Crit Care Med 2010;181:825–…

Modafinil effects during acute continuous positive airway pressure withdrawal: a randomized crossover double-blind placebo-controlled trial

SC Williams, NS Marshall, M Kennerson… - American Journal of …, 2010 - atsjournals.org
Modafinil treatment reduced steering variability and the mean RT to DA probes on the …
In this randomized placebo-controlled crossover trial, we show for the first time that modafinil

The effect of modafinil on cortical excitability in patients with narcolepsy: a randomized, placebo-controlled, crossover study

EY Joo, SB Hong, HJ Kim, YH Lim, DL Koo, KH Ji… - Sleep Medicine, 2010 - Elsevier
double-blind, randomized, crossover study, patients and controls received a single dose of
400 mg modafinilModafinil is a first-line pharmacological treatment for daytime sleepiness in …