significant interest in the development of effective imaging strategies. This work reports a
new multimodal bioimaging method for accurate and rapid diagnosis of cancer cells by
introducing aqueous Fe 2+ and Zn 2+ ions into cancer cells (ie, HeLa, U87, and HepG2
cancer cells). We found that the biocompatible metal ions Fe 2+ and Zn 2+ forced the cancer
cells to spontaneously synthesize fluorescent ZnO nanoclusters and magnetic Fe 3 O 4 …