Block copolymer self-assembly is normally conducted via post-polymerization processing at
high dilution. In the case of block copolymer vesicles (or “polymersomes”), this approach
normally leads to relatively broad size distributions, which is problematic for many potential
applications. Herein we report the rational synthesis of low-polydispersity diblock copolymer
vesicles in concentrated solution via polymerization-induced self-assembly using reversible
addition–fragmentation chain transfer (RAFT) polymerization of benzyl methacrylate. Our …