Due to the enormous benefits for human health, probiotics have gained popularity in the current era of science and have received a lot of public interest recently. Many bacterial strains have been used as probiotics for commercial applications. For a long time, the only yeast, Saccharomyces cerevisiae var. boulardii, was referred to be a probiotic. Interest in the probiotic potential of different yeast strains has grown in recent years. The purpose of the present review is to explore the updated information on the efficacy of various yeast strains as probiotics for human welfare.