Recognition of linear B-cell epitope of betanodavirus coat protein by RG-M18 neutralizing mAB inhibits giant grouper nervous necrosis virus (GGNNV) infection

CW Chen, MS Wu, YJ Huang, CA Cheng, CY Chang - PLoS One, 2015 - journals.plos.org
… The coat protein of Betanodavirus is the sole structural protein, and it can assemble the …
-titer neutralizing mAB, RG-M18, to identify the linear B-cell epitope on the viral coat protein. By …

Identification of b-cell epitopes on capsid protein reveals two potential neutralization mechanisms in red-spotted grouper nervous necrosis virus

Z Zhang, J Xing, X Tang, X Sheng, H Chi… - Journal of …, 2023 - Am Soc Microbiol
… To determine the minimal B-cell epitope-recognizing sites of MAbs 2B7 and 3A6, we … antigen
distribution patterns of betanodavirus, the molecular basis for neutralization, and viral entry-…

Comprehensive Linear Epitope Prediction System for Host Specificity in Nodaviridae

TC Shih, LP Ho, HY Chou, JL Wu, TW Pai - Viruses, 2022 - mdpi.com
… the mechanism is controlled by major capsid protein (MCP), we … B cell epitope datasets were
taken from SVMTrip_20AA [36], … In summary, the predicted epitopes for betanodavirus were …

石斑魚病毒之分子學研究: 乙型野田病毒線性B 細胞抗原決定區與虹彩病毒抗細胞凋亡CARD 蛋白

陳建文 - 2015 - airitilibrary.com
… The coat protein of betanodavirus is the sole structural protein, … -titer neutralizing mAB, RG-M18,
to identify the linear B-cell … that the linear epitope recognized by RG-M18 is located at the …

Recognition of linear B-cell epitope of Betanodavirus coat protein by RG-M18 neutralizing mAB inhibits giant grouper nervous necrosis virus (GGNNV) infection.

CCW Chen ChienWen, WMS Wu MingShan… - 2015 - cabidigitallibrary.org
… The coat protein of Betanodavirus is the sole structural protein, and it can assemble the …
-titer neutralizing mAB, RG-M18, to identify the linear B-cell epitope on the viral coat protein. By …

Peptide scanning-assisted identification of a monoclonal antibody-recognized linear B-cell epitope

CW Chen, CY Chang - Journal of Visualized Experiments …, 2017 - pmc.ncbi.nlm.nih.gov
… using a neutralizing mAb. This technique relies on the dot-blot … sequence at the Betanodavirus
coat protein epitope region. … was recognized by the RG-M18 mAb as an 8-mer peptide, …

[引用][C] Recognition of linear B-cell epitope of betanodavirus coat protein by RG-M18 neutralizing mAb inhibits giant grouper nervous necrosis virus infection

CY Chang, MS Wu, YJ Huang, CA Cheng, CW Chen - 2015 - ir.sinica.edu.tw
Recognition of linear B-cell epitope of betanodavirus coat protein by RG-M18 neutralizing
mAb inhibits giant grouper nervous necrosis virus infection | Scholars Hub of the Academia …

Identification of a novel linear B-cell epitope on the nucleocapsid protein of porcine deltacoronavirus

J Fu, R Chen, J Hu, H Qu, Y Zhao, S Cao… - International journal of …, 2020 - mdpi.com
… tested, all recognized the 122 C-terminal amino acids of the N-protein (aa 221-341), indicating
that this section contains the main antigenic epitope of N protein. IEDB (Immune Epitope

… antibody targeting the functional P-domain of Nervous Necrosis virus (NNV) coat protein: Developing an epitope-blocking ELISA to quantify viral neutralizing …

LCP Carmen, J Chan, SQ Lee, HY Hong, PX Chee… - Aquaculture, 2025 - Elsevier
… The capsid protein (∼42 kDa) comprises of an N-terminal arm (residues 1–51), a shell (S) …
Betanodavirus, is classified into four genotypes based on the capsid protein, which include …

Nervous necrosis virus coat protein mediates host translation shutoff through nuclear translocalization and degradation of polyadenylate binding protein

CA Cheng, JM Luo, MH Chiang, KY Fang… - Journal of …, 2021 - Am Soc Microbiol
… belongs to the genus Betanodavirus of the family Nodaviridae. … A monoclonal antibody
(RG-M18) against NNV coat protein … To neutralize the low pH, 5 μl neutralization buffer (0.5 M Tris-…