With the increased usage of Web 2.0 and data-affluent tools such as social media platforms and web blog services, the challenge of extracting public sentiment and disseminating personal health information has become more common than ever in the last decade. This paper proposes a novel model for Dengue disease detection based on social media posts alone. The model does not access any personal information of people or any medical record. The model extracts the presence of patients infected with Dengue disease based on tweets only and decides whether it is a general discussion about the disease, and no one is actually infected, or people are actually infected with that disease. The identification of people infected with Dengue is determined by clinical tests, but the propose technique is used for automatic surveillance and identification of regions where the spread is happening at an alarming rate and guide healthcare professional to take necessary actions to control the spread. This paper uses different machine/deep learning approaches to utilize tweets data for automatic and efficient disease detection. Experimental results demonstrate that the proposed model is able to achieve 92% accuracy compared to the current state-of-the-art techniques in this domain.