Rationale and Objectives To investigate for differences in metabolic concentrations and
ratios between patients with systemic lupus erythematosus (SLE) without (group SLE) and
those with neurological symptoms (group NPSLE) compared to a healthy control (group HC)
in three normal-appearing brain regions: the frontal white matter, right insula (RI), and
occipital gray matter and whether changes in any of the metabolites or metabolic ratios are
correlated to disease activity and other clinical parameters. Materials and Methods Twenty …