Reduction of the dose of radiotherapy to the elective neck in head and neck squamous cell carcinoma; a randomized clinical trial. Effect on late toxicity and tumor …
Background and purpose A multi-center prospective randomized clinical trial has been
performed investigating whether a reduction of the dose to the elective nodal sites in head
and neck cancer delivered by intensity modulated radiotherapy (IMRT) would result in a
reduction of late side effects without compromising tumor control. Materials and methods
Two hundred patients were included. The prescription dose to the elective nodal volumes
was a normalized iso-effective dose in 2 Gy fractions (NID 2Gy) of 50 Gy in the standard arm …
performed investigating whether a reduction of the dose to the elective nodal sites in head
and neck cancer delivered by intensity modulated radiotherapy (IMRT) would result in a
reduction of late side effects without compromising tumor control. Materials and methods
Two hundred patients were included. The prescription dose to the elective nodal volumes
was a normalized iso-effective dose in 2 Gy fractions (NID 2Gy) of 50 Gy in the standard arm …
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