Refraction‐enhanced x‐ray imaging of mouse lung using synchrotron radiation source

N Yagi, Y Suzuki, K Umetani, Y Kohmura… - Medical …, 1999 - Wiley Online Library
N Yagi, Y Suzuki, K Umetani, Y Kohmura, K Yamasaki
Medical physics, 1999Wiley Online Library
The low divergent x‐ray beam from the third‐generation synchrotron radiation source such
as SPring‐8 enables us to observe refraction of x rays that is in the range of microradians.
Under an experimental condition for which ray optics is a good approximation, we found that
the refraction produces a high‐contrast projection image of a mouse when it was recorded at
6.5 m behind the specimen. Especially, the lung is visualized far better than with the
conventional imaging which utilizes absorption of x rays. This is a promising new technique …
The low divergent x‐ray beam from the third‐generation synchrotron radiation source such as SPring‐8 enables us to observe refraction of x rays that is in the range of microradians. Under an experimental condition for which ray optics is a good approximation, we found that the refraction produces a high‐contrast projection image of a mouse when it was recorded at 6.5 m behind the specimen. Especially, the lung is visualized far better than with the conventional imaging which utilizes absorption of x rays. This is a promising new technique for the diagnosis of diseases in the human lung with a low radiation dose.
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