… falciparum 3D7S8.4.2 is a mutant parasite defective in VAR2CSA translation, despite a high
… var2csa transcript 9 . To identify the factors involved in regulation of VAR2CSA translation, …

… falciparum 3D7S8.4.2 is a mutant parasite defective in VAR2CSA translation, despite a high
… the var2csa transcript9. To identify the factors involved in regulation of VAR2CSA translation…

… between the parasite derived PfEMP1VAR2CSA proteins and the CSA proteoglycans. …
translation the VAR2CSA proteins, we identified PTEF (Plasmodium translation enhancing factor…

… While the binding properties of PfEMP1 are difficult to compare between strains, VAR2CSA
… Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor. …

… erythrocyte membrane protein 1 (PfEMP1). These proteins … the presence of Plasmodium
translation enhancing factor (PTEF). … Reports establishing translational regulation of the var2csa …

… Despite this, translational control of var2csa has been well documented, showing that …
translation enhancing factor (PTEF) contribute to the translational regulation of var2csa [11–…

… falciparum is a variant surface protein called PfEMP1. … shown to be involved in translation of
the var2csa mRNA (64). … effect of the var2csa uORF (64), reinforces a possible regulatory link …

… an endogenous plasmodium translation-enhancing factor (15… in regulating translation of the
var2csa-encoded PfEMP1, this … uORF in Plasmodium, to which a defined regulatory role had …

… is unclear, however PfEMP1 has been shown to be the major … , PTEF (Plasmodium
translation enhancing factor) appears to … to or beyond regulation of var2csa translation. A recent …

… This is accomplished by tightly regulated transcriptional control of … if the var2csa transcript
only translates the uORF, thus saving the metabolic cost of translating a full- length PfEMP1. …