Regulation of asymmetric cell division in mammalian neural stem and cancer precursor cells
M Daynac, CK Petritsch - … Cell Division in Development, Differentiation and …, 2017 - Springer
Stem and progenitor cells are characterized by their abilities to self-renew and produce
differentiated progeny. The balance between self-renewal and differentiation is achieved
through control of cell division mode, which can be either asymmetric or symmetric. Failure
to properly control cell division mode may result in premature depletion of the
stem/progenitor cell pool or abnormal growth and impaired differentiation. In many tissues,
including the brain, stem cells and progenitor cells undergo asymmetric cell division through …
differentiated progeny. The balance between self-renewal and differentiation is achieved
through control of cell division mode, which can be either asymmetric or symmetric. Failure
to properly control cell division mode may result in premature depletion of the
stem/progenitor cell pool or abnormal growth and impaired differentiation. In many tissues,
including the brain, stem cells and progenitor cells undergo asymmetric cell division through …
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