Studies in the past decade in the field have demonstrated the significance of cytokines in
regulating epithelial and endothelial cell junctions including tight and anchoring junctions in
multiple organs including the testis. There are mounting evidences in recent years that
cytokines play a crucial role in the restructuring of junctions at the Sertoli–Sertoli and Sertoli–
germ cell interface in the seminiferous epithelium during spermatogenesis. These earlier
studies, however, were focused on the effects of cytokines in maintaining the steady-state …