Regulation of cholesterol biosynthesis and lipid metabolism: A microRNA management perspective
A Bhattarai, EM Likos, CM Weyman, GC Shukla - Steroids, 2021 - Elsevier
Cellular disruption of lipid and cholesterol metabolism results in pathological processes
linked to metabolic and cardiovascular diseases. Classically, at the transcription stages, the
Cholesterol levels are controlled by two cellular pathways. First, the SREBP transcription
factor family controls Cholesterol biosynthesis via transcriptional regulation of critical rate-
limiting cholesterogenic and lipogenic proteins. Secondly, The LXR/RXR transcription factor
family controls cholesterol shuttling via transcriptional regulation of cholesterol transport …
linked to metabolic and cardiovascular diseases. Classically, at the transcription stages, the
Cholesterol levels are controlled by two cellular pathways. First, the SREBP transcription
factor family controls Cholesterol biosynthesis via transcriptional regulation of critical rate-
limiting cholesterogenic and lipogenic proteins. Secondly, The LXR/RXR transcription factor
family controls cholesterol shuttling via transcriptional regulation of cholesterol transport …
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