… Hypoxia-inducible factor-1α (HIF-1α) and vascular endothelial growth factor (VEGF) are
considered to be among the most important angiogenic factors [1]; therefore, inhibition of HIF-1α …

… signal, hypoxia-inducible factor-1 (HIF-1), and its downstream signal, vascular endothelial
growth factor (… Forty-eight control rats underwent similar surgical procedures without creating …

… (HIF-1α) and with hypoxia-inducible factor-2α (HIF-2α) and in … that this VEGF hypoxia-inducible
pathway regulated by HIF-1α … Therefore, the key upstream signal for VEGF regulation via …

… RT-PCR and Western blot show vascular endothelial growth factor (VEGF) expression
after 1.5-h MCA occlusion at different reperfusion time points. (A) Reverse transcriptase-…

… by up-regulating the expression of vascular endothelial growth factor (VEGF). We … and
growth of pancreatic cancer in vivo and sought to identify major signaling pathways regulated by …

… Vascular endothelial growth factor (VEGF) is one of the genes upregulated by HIF‐1 and
is … aberrant activation of hypoxia inducible factor‐1α/vascular endothelial growth factor (HIF‐1α/…

… vascular endothelial growth factor (VEGF), a key factor modulating angiogenesis [6]. In
addition, PHDs (PHD2 and PHD3) are hypoxia-inducible … the growth factor signals upstream of …

… the expression of vascular endothelial growth factor (VEGF) and hypoxia inducible factor‑1
(HIF‑1… of target genes, HIF-1 is considered to be the low oxygen related regulatory gene in the …

… hypoxia inducible factor (HIF)-1α → hypoxia response element (HRE) → VEGF signaling …
(c)post-transcriptional regulation is as important as transcriptional regulation in many genes …

… VEGF expression is regulated by cellular hypoxia mediated by hypoxia inducible … is known
to alter the regulation of various intracellular signal transduction pathways. Mutations of p53 …