The aim of this study was to reveal the relationships between structure elements of
flavonoids and their antileukemic activity. The human leukemia cell line K562 as a model of
blast crisis of chronic myeloid leukemia and a set of 18 different flavonoids from four
flavonoid subfamilies were used for researching these relationships. Relationships between
structure and antiproliferative, proapoptotic, and differentiation activities of flavonoids were
estimated by pairwise comparative analysis of selected flavonoids that differ in one structure …