Resonance enhanced AFM-IR: A new powerful way to characterize blooming on polymers used in medical devices
A Dazzi, J Saunier, K Kjoller, N Yagoubi - International Journal of …, 2015 - Elsevier
A Dazzi, J Saunier, K Kjoller, N Yagoubi
International Journal of Pharmaceutics, 2015•ElsevierIn this paper we demonstrated the application of resonance enhanced AFM-IR to the study
of the medical device surfaces. Surface state is one of the most important parameter on the
biocompatibility of an implantable medical device. By using this new technique, it was
possible to obtain with high resolution topographic and chemical maps and to identify the
chemical nature of very thin deposit observed on the surface. This was illustrated with the
case of lubricant exudation on polyurethane used in the making of implantable catheters.
of the medical device surfaces. Surface state is one of the most important parameter on the
biocompatibility of an implantable medical device. By using this new technique, it was
possible to obtain with high resolution topographic and chemical maps and to identify the
chemical nature of very thin deposit observed on the surface. This was illustrated with the
case of lubricant exudation on polyurethane used in the making of implantable catheters.
Abstract
In this paper we demonstrated the application of resonance enhanced AFM-IR to the study of the medical device surfaces. Surface state is one of the most important parameter on the biocompatibility of an implantable medical device. By using this new technique, it was possible to obtain with high resolution topographic and chemical maps and to identify the chemical nature of very thin deposit observed on the surface. This was illustrated with the case of lubricant exudation on polyurethane used in the making of implantable catheters.
Elsevier
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