Resveratrol represses tumor necrosis factor α/c-Jun N-terminal kinase signaling via autophagy in human dental pulp stem cells
Objectives: To study the effects of polyphenol resveratrol on TNFα-induced inflammatory
signaling as well as the underlying mechanism in human dental pulp stem cells (DPSCs).
Materials and methods: Human DPSCs were cultured and treated by TNFα in the presence
or absence of resveratrol. NF-κB and mitogen-activated protein kinase (MAPK) signaling
pathways were analyzed by Western blotting and immunofluorescence staining. Interleukin
6 (IL6) and interleukin 8 (IL8) mRNA levels were analyzed by reverse transcription …
signaling as well as the underlying mechanism in human dental pulp stem cells (DPSCs).
Materials and methods: Human DPSCs were cultured and treated by TNFα in the presence
or absence of resveratrol. NF-κB and mitogen-activated protein kinase (MAPK) signaling
pathways were analyzed by Western blotting and immunofluorescence staining. Interleukin
6 (IL6) and interleukin 8 (IL8) mRNA levels were analyzed by reverse transcription …
Resveratrol represses tumor necrosis factor α/c-Jun N-terminal kinase signaling via autophagy in human dental pulp stem cells.
WFM Wang FengMing, HZ Hu Zhiai, LXH Liu XiaoHua… - 2019 - cabidigitallibrary.org
Objectives: To study the effects of polyphenol resveratrol on TNFα-induced inflammatory
signaling as well as the underlying mechanism in human dental pulp stem cells (DPSCs).
Materials and methods: Human DPSCs were cultured and treated by TNFα in the presence
or absence of resveratrol. NF-κB and mitogen-activated protein kinase (MAPK) signaling
pathways were analyzed by Western blotting and immunofluorescence staining. Interleukin
6 (IL6) and interleukin 8 (IL8) mRNA levels were analyzed by reverse transcription …
signaling as well as the underlying mechanism in human dental pulp stem cells (DPSCs).
Materials and methods: Human DPSCs were cultured and treated by TNFα in the presence
or absence of resveratrol. NF-κB and mitogen-activated protein kinase (MAPK) signaling
pathways were analyzed by Western blotting and immunofluorescence staining. Interleukin
6 (IL6) and interleukin 8 (IL8) mRNA levels were analyzed by reverse transcription …