Rhamnolipid biosurfactants—Possible natural anticancer agents and autophagy inhibitors

S Semkova, G Antov, I Iliev, I Tsoneva, P Lefterov… - Separations, 2021 - mdpi.com
Background/Aim: A number of biologically active substances were proved as an alternative
to conventional anticancer medicines. The aim of the study is in vitro investigation of the
anticancer activity of mono-and di-Rhamnolipids (RL-1 and RL-2) against human breast
cancer. Additionally, the combination with Cisplatin was analyzed. Materials and Methods:
Breast cell lines (MCF-10A, MCF-7 and MDA-MB-231) were treated with RLs and in
combination with Cisplatin. The viability was analyzed using MTT assay, and investigation of …

[引用][C] Rhamnolipid biosurfactants: Possible natural anticancer agents and autophagy inhibitors. Separations 8, 1–14

S Semkova - 2021
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