[PDF][PDF] Risk factors associated with amputation-free survival in patient with diabetic foot ulcers
SH Won, CY Chung, MS Park, T Lee… - Yonsei medical …, 2014 - synapse.koreamed.org
Yonsei medical journal, 2014•synapse.koreamed.org
Purpose To determine the 1-year survival rate, 1-year amputation-free survival rate and the
risk factors of amputation for patients with diabetic foot ulcers. Materials and Methods One
hundred seventy-three patients with diabetic foot ulcers were included in our study. Mean
patient age was 67.5 (range, 29 to 87, SD±11.4) years. 74% of the patients were male. Time
from study entry to amputation and time to death were evaluated separately as censored
event times by Kaplan-Meier curves and log-rank tests. A multivariate Cox proportional …
risk factors of amputation for patients with diabetic foot ulcers. Materials and Methods One
hundred seventy-three patients with diabetic foot ulcers were included in our study. Mean
patient age was 67.5 (range, 29 to 87, SD±11.4) years. 74% of the patients were male. Time
from study entry to amputation and time to death were evaluated separately as censored
event times by Kaplan-Meier curves and log-rank tests. A multivariate Cox proportional …
Purpose
To determine the 1-year survival rate, 1-year amputation-free survival rate and the risk factors of amputation for patients with diabetic foot ulcers.
Materials and Methods
One hundred seventy-three patients with diabetic foot ulcers were included in our study. Mean patient age was 67.5 (range, 29 to 87, SD ±11.4) years. 74% of the patients were male. Time from study entry to amputation and time to death were evaluated separately as censored event times by Kaplan-Meier curves and log-rank tests. A multivariate Cox proportional hazards regression analysis was carried out for determining the risk factors of amputation.
Results
The survival rate and amputation-free survival rate were 96.5% (n=167), 65.9% (n=114), respectively, over one year study period. Severity of ulcer was the strongest significant risk factor of amputation [hazard ratio (HR): 7.99; confidence interval (CI): 3.12 to 20.47]. Peripheral artery disease was also independent risk factor of amputation (HR: 2.64; CI: 1.52 to 4.59).
Conclusion
In assessing the prognosis of diabetic foot ulcers, clinicians should consider the severity of ulcer and presence of peripheral artery disease. Our study provides important insights into clinical practice and supplementary information for both physicians and patients.
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