Role of ARBs and ACEIs in the treatment of SARS-COV2

SM Hassan, AN Abbas, MH Mohammed… - European Journal of …, 2020 - clok.uclan.ac.uk
The coronavirus 2 (SARS‐CoV‐2) induces severe acute respiratory distress syndrome
(ARDS) via the coronavirus receptor angiotensin‐converting enzyme 2 (ACE2) in the host
cell to facilitate entry into the lungs Over activation of the renin‐angiotensin system (RAS)
and the down regulation of ACE2 expression are involved in SARS‐CoV induced lung
injury. RAS is the main system that has a regulatory roleinmaintaining electrolyte balance,
blood pressure, vascular tone and cardiovascular remodeling in the body. Angiotensin II …

[PDF][PDF] ROLE OF ARBs AND ACEIs IN THE TREATMENT OF SARS-COV2

JS Singh, NR Hadi - researchgate.net
The coronavirus 2 (SARS‐CoV‐2) induces severe acute respiratory distress syndrome
(ARDS) via the coronavirus receptor angiotensin‐converting enzyme 2 (ACE2) in the host
cell to facilitate entry into the lungs Over activation of the renin‐angiotensin system (RAS)
and the down regulation of ACE2 expression are involved in SARS‐CoV induced lung
injury. RAS is the main system that has a regulatory roleinmaintaining electrolyte balance,
blood pressure, vascular tone and cardiovascular remodeling in the body. Angiotensin II …
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