Role of red-Ox cycle in structural oscillations and solvation dynamics in the mitochondria of a live cell
Structural oscillations and solvation dynamics in the mitochondria of a live cell are studied
by time-resolved microscopy using a covalent fluorescence probe. We compared the
dynamics in a human breast cancer cell (MCF-7) with that in a normal breast cell MCF-10A.
The probe, CPM (7-diethylamino-3-(4-maleimido-phenyl)-4-methylcoumarin), binds with the
free thiol groups. In MCF-10A cell, CPM binds with the discrete mitochondria. In MCF-7,
CPM labels the clustered mitochondria in the peri-nuclear region. Location of the CPM in the …
by time-resolved microscopy using a covalent fluorescence probe. We compared the
dynamics in a human breast cancer cell (MCF-7) with that in a normal breast cell MCF-10A.
The probe, CPM (7-diethylamino-3-(4-maleimido-phenyl)-4-methylcoumarin), binds with the
free thiol groups. In MCF-10A cell, CPM binds with the discrete mitochondria. In MCF-7,
CPM labels the clustered mitochondria in the peri-nuclear region. Location of the CPM in the …
[引用][C] Role of Red-Ox Cycle in Structural Oscillations and Solvation Dynamics in the Mitochondria of a Live Cell
C Shyamtanu, C Rajdeep, DS Kumar, JS Sankar… - 2015
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