Role of shear stress in ventilator-induced lung injury
We read with interest the article by Ary Serpa Neto and colleagues, 1 which reported that
high driving pressure during intraoperative ventilation and a change in the level of positive
end expiratory pressure (PEEP) that results in an increase in driving pressure are
associated with more pulmonary complications after surgery. An increase in the level of
PEEP could theoretically lead to a decrease in driving pressure when tidal volume is
constant. With regards to an increase in driving pressure due to increased PEEP levels …
high driving pressure during intraoperative ventilation and a change in the level of positive
end expiratory pressure (PEEP) that results in an increase in driving pressure are
associated with more pulmonary complications after surgery. An increase in the level of
PEEP could theoretically lead to a decrease in driving pressure when tidal volume is
constant. With regards to an increase in driving pressure due to increased PEEP levels …
[HTML][HTML] Role of shear stress in ventilator-induced lung injury–Authors' reply
4 Protti A, Maraffi T, Milesi M, et al. Role of strain rate in the pathogenesis of ventilator-
induced lung edema. Crit Care Med 2016; DOI: 10.1097/CCM. 0000000000001718. 5
Cressoni M, Gotti M, Chiurazzi C, et al. Mechanical power and development of ventilator-
induced lung Injury. Anesthesiology 2016; 124: 1100–08.
induced lung edema. Crit Care Med 2016; DOI: 10.1097/CCM. 0000000000001718. 5
Cressoni M, Gotti M, Chiurazzi C, et al. Mechanical power and development of ventilator-
induced lung Injury. Anesthesiology 2016; 124: 1100–08.
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